Game Details:
Matchup: Bears vs Cowboys
Date & Time: Sunday, September 21, 2025 | 8:20 PM ET
Venue: AT&T Stadium, Arlington, TX
Betting Line: Cowboys -7.5 | Over/Under: 44.5
Key Storylines
Cowboys Eyeing Strong Start: After an NFC Divisional Round exit last season, Cowboys are back with a vengeance and looking to make a statement at home. Quarterback Dak Prescott is coming off a 3-touchdown performance in Week 2 and has developed strong chemistry with CeeDee Lamb and newcomer tight end Brock Bowers.
Bears Riding Rookie QB: The Bears handed the reins to rookie quarterback Caleb Williams this season, and so far, it’s been a rollercoaster. He’s shown flashes of brilliance but also rookie growing pains under pressure. Against a fierce Cowboys pass rush, it’s going to be a gut-check game for the Bears’ offensive line.
Micah Parsons vs Chicago’s Offensive Line: All eyes will be on how Chicago protects their young quarterback from Parsons, who’s already racked up 4 sacks through the first two weeks. He could be the ultimate game-wrecker in this matchup.
Injury Report
Bears:
Questionable: DJ Moore (hamstring), Kyler Gordon (concussion)
Out: Teven Jenkins (shoulder)
Cowboys:
Questionable: Tony Pollard (ankle), Zack Martin (calf)
Probable: Brandin Cooks (knee)
Betting Trends
- Cowboys are 10-2 ATS in their last 12 home games.
- Bears are 1-6 ATS in their last 7 games as an underdog.
- The Under has hit in 5 of the last 6 meetings between these two teams.
- Cowboys have covered the spread in 4 straight games as a favorite.
Player Props to Watch
Caleb Williams – Passing Yards: 220.5
If the Bears fall behind early, Williams could surpass this mark on volume alone. However, turnovers could be a concern with Dallas’ ball-hawking secondary.
CeeDee Lamb – Receiving Yards: 85.5
He’s hit the over in both games this season and is getting double-digit targets per game. Against a shaky Bears secondary, this prop could cash early.
Prediction & Best Bets
Spread: Cowboys -7.5 → Dallas has the better roster and a ferocious defense that should overwhelm the Bears’ rookie QB.
Total: Under 44.5 → With a rookie QB in hostile territory and the Cowboys’ defense dictating tempo, expect a lower-scoring affair.
Player Prop: CeeDee Lamb Over 85.5 receiving yards → Chicago simply doesn’t have an answer for him.
The Cowboys have a clear talent edge on both sides of the ball, and at home, they’re a tough out. Unless Caleb Williams has a breakout game, it’s hard to see the Bears keeping pace with Dallas’ balanced attack. Expect the Cowboys to dominate in primetime.
Final Score Prediction: Cowboys 27, Bears 16
