Cowboys vs Packers Betting Preview & Prediction | SIT Picks

Game Details:
Matchup: Packers vs Cowboys
Date & Time: Sunday, September 28, 2025 | 8:20 PM ET
Venue: AT&T Stadium, Arlington, TX
Betting Line: Cowboys -4.5 | Over/Under: 47.5

Key Storylines

Playoff Implications Start Early: While it’s only Week 4, this NFC showdown could have significant postseason implications. Both the Packers and Cowboys are 2-1 entering this matchup, looking to gain ground in their respective divisions.

Jordan Love Continues to Impress: The Packers’ QB has started hot in 2025, throwing for over 700 yards and 6 touchdowns through three games. He’s avoided turnovers and shown command of Matt LaFleur’s offense.

Cowboys Bounce Back at Home: After a tough loss on the road to Philadelphia last week, the Cowboys are eager to get back on track. Dak Prescott and the defense will look to capitalize on home field advantage, where they’ve won 8 of their last 10 games.

Injury Report

Packers:
– Questionable: Christian Watson (hamstring)
– Out: Eric Stokes (ankle), Luke Musgrave (concussion)

Cowboys:
– Questionable: Brandin Cooks (knee), Leighton Vander Esch (neck)
– Out: Tyler Biadasz (ankle), DeMarvion Overshown (knee)

Betting Trends

Against the Spread (ATS):
Packers: 2-1 ATS this season
Cowboys: 1-2 ATS this season

Over/Under Trends:
– The total has gone under in 2 of the Packers’ 3 games
– The total has gone over in all 3 of Cowboys’ games

Historical Edge: Green Bay has won four straight meetings against Dallas, including a wild-card playoff win last season. Can Dallas finally flip the script at home?

Player Props to Watch

Jordan Love (Packers) – Passing Yards Total: 234.5
With Watson potentially sidelined, Love may have to depend more on Romeo Doubs and rookie Dontayvion Wicks. Still, expect high volume through the air.

CeeDee Lamb (Cowboys) – Receiving Yards Total: 86.5
Lamb continues to be Prescott’s go-to threat. He could have a big night against a Packers secondary missing key pieces.

Prediction & Best Bets

Spread: Cowboys -4.5 → Dallas has the defensive talent to challenge Love and force mistakes. Their dominance at AT&T Stadium makes them the safer bet.

Total: Over 47.5 → With both offenses capable of scoring in bunches and some injuries on defense, the over is an appealing play.

Player Prop: CeeDee Lamb Over 86.5 receiving yards → Expect him to shine in primetime.

Final Score Prediction: Cowboys 28, Packers 23

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