Game Details:
Matchup: Lions vs. Eagles
Date & Time: Sunday, November 16, 2025 | 8:20 PM ET
Venue: Lincoln Financial Field, Philadelphia, PA
Betting Line: Eagles -3.5 | Over/Under: 47.5
Key Storylines
NFC Heavyweight Clash: Sunday night’s primetime showdown pits two NFC contenders against one another. The Eagles (7-2) are flying high atop the NFC East, while the Lions (6-3) continue to press their case as legitimate Super Bowl hopefuls out of the NFC North. A win here could have major implications for playoff seeding.
Hurts vs. Goff: Jalen Hurts and Jared Goff have both enjoyed strong 2025 campaigns. Hurts continues to be a dual-threat menace for Philadelphia, while Goff has benefitted from a top-five offensive line and a steadily producing run game behind David Montgomery and Jahmyr Gibbs.
Trenches Battle: The Lions boast one of the league’s best offensive lines, but they’ll be up against a fierce Eagles pass rush led by Haason Reddick and rookie Jalen Carter, who leads all defensive tackles in sacks this season (6 sacks through 9 games).
Injury Report
Lions:
Questionable: Frank Ragnow (toe), Amon-Ra St. Brown (ankle)
Out: James Houston (ankle – IR), Emmanuel Moseley (knee – IR)
Eagles:
Questionable: Dallas Goedert (forearm), Darius Slay (knee)
Out: Nakobe Dean (foot – IR), Avonte Maddox (pectoral – IR)
Betting Trends
Against the Spread (ATS):
Lions: 5-4 ATS this season
Eagles: 4-5 ATS this season
Over/Under Trends:
The total has gone over in 6 of the Lions’ 9 games
The total has gone under in 5 of the Eagles’ 9 games
Road Warriors: The Lions are 3-1 on the road this season, including a key win at Dallas. Meanwhile, the Eagles are unbeaten at home (4-0), and their crowd at Lincoln Financial Field has been a major factor.
Player Props to Watch
Amon-Ra St. Brown (Lions) – Receiving Yards Total: 75.5
St. Brown has been a model of consistency when healthy. If he plays, Detroit’s offense is at another level. He’s gone over 75 yards in six of eight games played.
D’Andre Swift (Eagles) – Rushing Yards Total: 54.5
Revenge game for Swift, who was traded from Detroit to Philly in 2023. The Lions rank just 21st in rush defense, so this could be a breakout spot.
Prediction & Best Bets
Spread: Eagles -3.5 → Two high-powered offenses collide, but Philadelphia’s home dominance and deeper defensive front should make the difference in a close game. The half-point hook makes it risky, but we’re backing the Eagles at home.
Total: Over 47.5 → Both offenses are capable of putting up points quickly, and turnovers may help tilt the total toward the over in what could be a back-and-forth affair.
Player Prop: Amon-Ra St. Brown Over 75.5 receiving yards → If active, he profiles as Detroit’s go-to target in a potential shootout.
Final Score Prediction: Eagles 27, Lions 23
